HLA-DR AntigensA group of D-related human leukocyte antigens that are polymorphic glycoproteins found on lymphoid cells. They consist of alpha and beta chains and their inheritance differs from that of the DQ and DP antigens; their presence seems to be associated with certain skin diseases like pemphigus vulgaris, dermatitis herpetiformis, and type I diabetes.
AntigensSubstances that are recognized by the immune system and induce an immune reaction.
GlycoproteinsConjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.
SkinThe outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
PemphigusGroup of chronic blistering diseases characterized histologically by acantholysis and blister formation within the epidermis.
DermatitisAny inflammation of the skin.
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