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Calcimycin

An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.


Streptomyces

A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.

Cations

Positively charged atoms, radicals or groups of atoms which travel to the cathode or negative pole during electrolysis.

Membranes

Thin layers of tissue which cover parts of the body, separate adjacent cavities, or connect adjacent structures.

Phosphorylation

The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.

Liver

No Entry for Liver

Role

The expected and characteristic pattern of behavior exhibited by an individual as a member of a particular social group.

Cations

Positively charged atoms, radicals or groups of atoms which travel to the cathode or negative pole during electrolysis.



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